Dobucard Dosage/Direction for Use

Dobutamine is given as the hydrochloride but doses are expressed in terms of the base. It is administered by intravenous infusion as a dilute solution (0.25 to 5 mg per mL), in glucose 5% or sodium chloride 0.9%; other fluids may also be suitable.
In the management of acute heart failure, Dobutamine is given at a usual rate of 2.5 to 10 mcg per kg body-weight per minute, according to the patient’s heart rate, blood pressure, cardiac output, and urine output. A range of 0.5 up to 40 mcg per kg per minute has occasionally been required. It has been recommended that treatment with Dobutamine should be discontinued gradually.
Dobutamine is also employed as an alternative to exercise in cardiac stress testing. A solution containing 1 mg per mL is employed for this purpose, administered via an infusion pump. A dose of 5 mcg per kg per minute is infused for 8 minutes; the dose is then increased by increments of 5 mcg per kg per minute up to a usual maximum of 20 mcg per kg per minute, with each dose being infused for 8 minutes before the next incremental increase; higher doses of up to 40 mcg per kg per minute have sometimes been employed.
Or prescribed by a physician.