Dobucard Special Precautions

Dobutamine HCl should be used with caution in patients with acute myocardial infarction, and in cardiogenic shock complicated by severe hypotension. Hypovolemia should be corrected before treatment using Dobutamine.
Dobutamine should also be used with great caution in patients who may be particularly susceptible to its cardiovascular actions, notably those with pre-existing arrhythmias or tachycardia, Prinzmetal's angina, thromboembolic disorders, or a history of ischemic heart disease. Extreme care is also needed in conditions which predispose a patient to adverse effects on the heart, such as hyperthyroidism; elevated thyroid hormone concentrations may also enhance receptor sensitivity. Special care is also needed in the elderly who may have pre-existing coronary or cerebrovascular disease.
Interference with diagnostic tests is caused by Dobutamine. Contamination of blood samples with Dobutamine has been reported to produce falsely decreased creatinine values in an enzymatic test.