Adverse reactions are listed as follows by system organ class and frequency. Frequencies are defined as: Very common (≥1/10), Common (≥1/100 to <1/10), Uncommon (≥1/1,000 to <1/100), Rare (≥1/10,000 to <1/1000), Very rare (<1/10,000), Not known (cannot be estimated from the available data). (See table.)
![](https://mpfshstrg.blob.core.windows.net/mpf-uat-common-resources/Images/monograph/table.gif)
Systemic effects of some nasal corticosteroids may occur, particularly when administered at high doses for prolonged periods.
Growth retardation has been reported in children receiving nasal corticosteroids. Growth retardation may be possible in adolescents, too.
In rare cases osteoporosis was observed if nasal glucocorticoids were administered long-term.
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