Injection: Caution is required when administering Hemotrex concomitantly with hemocoagulase because such combination in large doses may increase the potential for thrombus formation.
Others: Long-term administration of large dose of Hemotrex has been reported to be associated with change in retina in dogs.
Hemotrix has been reported to be incompatible with following drugs given by injection; reserpine, methyl and ethyl testosterone, lipid and tissue thromboplastin, sulfadimethoxine.
Some animal studies have shown that concomitant IV administration of Hemotrex with lipid thromboplastin in large doses has caused thrombus formation.