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Tablet: Tranexamic acid is an antifibrinolytic agent used mainly in the treatment and prophylaxis of hemorrhage associated with excessive fibrinolytic. It is given by mouth or by slow IV injection, limited due to gastrointestinal disturbances; hypotension has occurred, particularly after rapid IV infusion.
Pharmacokinetics: Tranexamic acid is rapidly absorbed from the gastrointestinal tract: absorption is 30-50%. It is widely distributed throughout the body, diffuses across the placenta and has been detected in breast milk. It has a plasma elimination half-life of about 2 hrs. It is excreted in the urine mainly as unchanged drug.
