Istan Adverse Reactions

The most common adverse effects occurring with Mefenamic Acid are gastro-intestinal disturbances including diarrhea, nausea, vomiting, and abdominal pain. Peptic ulceration and gastro-intestinal bleeding have also been reported. Headache, drowsiness, dizziness, nervousness, and visual disturbances have been reported. There may be hypersensitivity reactions including skin rashes and urticaria, and occasionally allergic glomerulonephritis; asthma may be precipitated. Reported hematological effects include hemolytic anemia, agranulocytosis, pancytopenia, thrombocytopenia or thrombocytopenic purpura, and bone-marrow aplasia. Renal failure, glomerulonephritis and papillary necrosis have been reported. Therapy should be discontinued if diarrhea or skin rash occur.