Acute maxillary sinusitis 500 mg once daily for 10-14 days. Acute bacterial exacerbation of chronic bronchitis 500 mg once daily for 7 days. Nosocomial pneumonia 750 mg once daily for 7 days. Community-acquired pneumonia 500 mg once daily or bid for 7-14 days or 750 mg once daily for 5 days. Complicated UTI 250 mg once daily for 7-10 days. Uncomplicated UTI 250 mg once daily for 3 days. Acute pyelonephritis 250 mg once daily for 10 days. Complicated skin & skin structure infection 750 mg once daily for 7-14 days. Uncomplicated skin & skin structure infection 500 mg once daily for 7-10 days. Chronic bacterial prostatitis 500 mg once daily for 28 days.
Discontinue use if patients experience tendon pain, inflammation or rupture. Avoid excessive alkalinity of urine due to risk of crystalluria; exposure to strong sunlight or sunlamps. Avoid use in patients w/ aortic aneurysm or at risk for an aortic aneurysm eg, patients w/ peripheral atherosclerotic vascular disease, HTN, certain genetic conditions (eg, Marfan syndrome & Ehlers-Danlos syndrome) & elderly. Patients w/ G6PD deficiency or myasthenia gravis. May impair ability to drive or operate machinery. Hepatic or renal impairment. Not to be used during pregnancy & lactation & in children & adolescents.
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