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Hypersensitivity to GnRH, GnRH agonist analogs or its diluent.
Undiagnosed abnormal vaginal bleeding.
Leuprorelin Acetate (Luprodex) 3.75 mg Depot is contraindicated in women who are pregnant while receiving the drug. Leuprorelin Acetate (Luprodex) 3.75 mg Depot may cause fetal harm when administered to a pregnant woman.
Use in women who are breast-feeding.
