IDDM; heart failure, MI, dehydration, acute or chronic alcoholism or any other conditions predisposing to lactic acidosis; renal impairment, liver failure.
May increase the risk of hypoglycemia w/ drugs that decrease blood glucose conc. May reduce efficacy w/ drugs that increase blood glucose conc. May increase the risk of lactic acidosis & hypoglycemia. Care when given concomitantly w/ drugs that may impair renal function.
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