Depression, generalized & social anxiety disorders 10 mg once daily, increased after at least 1 wk up to a max of 20 mg once daily. Panic disorder w/ or w/o agoraphobia Initially 5 mg once daily, may be increased after 1 wk to 10 mg once daily up to a max of 20 mg daily. Patient w/ hepatic impairment or those who are poor metabolizers w/ CYP2C19 isoenzyme Initially 5 mg daily, may be increased to 10 mg daily after 2 wk.
Patients w/ active or history of epilepsy; cardiac disease or history of bleeding disorders; diabetes; angle-closure glaucoma; those receiving ECT. Discontinue if seizure develops.
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