Nikem Special Precautions

Hepatic Impairment: Nicardipine should be used with particular caution in these patients. It is recommended to use the same dose regimens as for elderly patients in patients with impaired liver function or reduced hepatic blood flow.
Renal Impairment: Nicardipine should be used with particular caution in these patients. It is recommended to use the same dose regimens as for elderly patients in patients with renal impairment.
Use in Children: Nicardipine Hydrochloride Injection safety and efficacy has not been established in low birth weight infants, newborns, nursing infants, infants, and children.
Nicardipine should only be used for life-threatening hypertension in pediatric intensive care settings or post-operative contexts.
Initial dose: In case of emergency, a starting dose of 0.5 to 5 mcg/kg/min is recommended.
Maintenance dose: The maintenance dosage of 1 to 4 mcg/kg/min is recommended.
Nicardipine should be used with particular caution in children with renal impairment. In this case, only the lowest posology should be used.