Nophlegm Dosage/Direction for Use

200 mg: Acetylcysteine is used for its mucolytic activity in respiratory disorders associated with acute cough. It can be given by nebulisation of 3 to 5 mL of 20% solution or 6 to 10 mL of a 10% solution through a face mask or mouthpiece 3 or 4 times daily. Acetylcysteine has been given by mouth in doses of 200 mg two or three times daily as granules or effervescent dissolved in 30 mL of water. Children aged 1 month to 2 years may be given 100 mg twice daily, and those aged 2 to 7 years 200 mg twice daily.
Acetylcysteine is given by intravenous infusion or by mouth in the treatment of paracetamol poisoning. If given intravenously, 150 mg/kg of Acetylcysteine in 200 mL of glucose 5% is given initially over 15 minutes, followed by infusion of 50 mg/kg in 500 mL of glucose 5% over the next 4 hours and then 100 mg/kg in one liter of glucose 5% over the next 16 hours. Sodium chloride 0.9% maybe used where glucose 5% is unsuitable.
Burns, children with inhalation injury who were treated with aerosolised heparin 5000 units alternating with 3 mL of 20% Acetylcysteine solution, inhaled every 2 hours for the 1st 7 days after injury, appeared to have significantly reduced mortality and reintubation rates compared with historical control. Or as prescribed by the physician.
600 mg: Empty sachet in a glass of water, stir with spoon. If necessary and drink immediately.
Adult: 600 mg daily or 200 mg twice a day or three times a day.
Children: 100 mg twice a day or four times a day according to age or as prescribed by the physician.