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Generalized urticaria has been observed in patients receiving Acetylcysteine for acetaminophen overdose. If this occurs or other allergic symptoms appear, treatment with Acetylcysteine should be discontinued unless it is deemed essential and the allergic symptoms can be otherwise controlled.
If encephalopathy due to hepatic failure becomes evident, Acetylcysteine treatment should be discontinued to avoid further administration of nitrogenous substances.
There are no data indicating that Acetylcysteine influences hepatic failure, but this remains a theoretical possibility.
