Nutrifat Dosage/Direction for Use

Nutrifat should be administered as a part of intravenous nutrition via peripheral vein or by central venous infusion.
Adult patients: The initial rate of infusion in adults should be 1 ml/minute for the first 15 to 30 minutes of infusion. If no untoward reactions occur (see Adverse Reactions), the infusion rate can be increased to 2 ml/minute. Not more than 500 ml of Nutrifat should be infused into adults on the first day of therapy. If the patient has no untoward reactions, the dose can be increased on the following day. The daily dosage should not exceed 2.5 g of fat/kg of body weight (25 ml of Nutrifat per kg). Nutrifat should make up no more than 60% of the total caloric input to the patient. Carbohydrate and a source of amino acids should comprise the remaining caloric input.
Pediatric patients: The dosage for premature infants starts at 0.5 g fat/kg body weight/24 hours (5 ml Nutrifat) and may be increased in relation to the infant's ability to eliminate fat. The maximum dosage recommended by the American Academy of Pediatrics is 3 g fat/kg/24 hours. The initial rate of infusion in older pediatric patients should be no more than 0.1 ml/minute for the first 10 to 15 minutes. If no untoward reactions occur, the rate can be changed to permit infusion of 1 ml of Nutrifat/kg/hour. The daily dosage should not exceed 3 g of fat/kg of body weight. Nutrifat should make up no more than 60% of the total caloric input to the patient. Carbohydrate and a source of amino acids should comprise the remaining caloric input.