312.5 mg powd for susp Childn Usual recommended dose: 25 mg/kg/day in divided doses every 8 hr,
>6 yr weighing 18-40 kg 5 mL tid,
1-6 yr weighing 10-18 kg 5 mL of 156.25 mg/5 mL susp tid,
<1 yr weighing 7.5 kg 2 mL of 156.25 mg/5 mL susp tid,
<1 yr 25 mg/kg/day.
Childn <40 kg Renal impairment CrCl 10-30 mL/min 15 mg/3.75 mg/kg bid. Max: 500 mg/125 mg bid,
CrCl <10 mL/min 15 mg/3.75 mg/kg as single daily dose. Max: 500 mg/125 mg.
Hemodialysis 15 mg/3.75 mg/kg/day once daily given prior to hemodialysis. Another dose may be given after hemodialysis to restore circulating drug levels.
457 mg powd for susp Adults & childn ≥40 kg Use adult formulations of amoxicillin/clavulanic acid.
Childn <40 kg Lower dose: 25 mg/3.6 mg/kg/day to 45 mg/6.4 mg/kg/day in 2 divided doses. Max daily dose: 1,000-2,800 mg amoxicillin & 143-400 mg clavulanic acid.
Some infections including otitis media, sinusitis & lower resp tract infection 45 mg/6.4 mg/kg/day to 70 mg/10 mg/kg/day in 2 divided doses.
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