Piperacillin/tazobactam is indicated for the treatment of the following infections in adults and children over 2 years of age (see Dosage & Administration and Pharmacology: Pharmacodynamics under Actions):
Adults and adolescents: Severe pneumonia including hospital-acquired and ventilator-associated pneumonia Complicated urinary tract infections (including pyelonephritis).
Complicated intra-abdominal infections.
Complicated skin and soft tissue infections (including diabetic foot infections).
Treatment of patients with bacteraemia that occurs in association with, or is suspected to be associated with, any of the infections listed above.
Piperacillin/tazobactam may be used in the management of neutropenic patients with fever suspected to be due to a bacterial infection.
Children 2 to 12 years of age: Complicated intra-abdominal infections.
Piperacillin/tazobactam may be used in the management of neutropenic children with fever suspected to be due to a bacterial infection.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.