Adult Hypertension: The usual dose is 50 mg once daily. The dose may be increased if necessary to 100 mg daily as a single dose or in two divided doses. An initial dose of 25 mg once daily should be given to patients with intravascular fluid depletion.
Heart Failure: The initial dose for patients with heart failure is 2.5 mg once a day. The dose may be increased by 1.25 mg at week's interval to the usual maintenance dose of 50 mg once a day or as the patient can tolerate. Or as prescribed by the physician.