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The fixed dose combination of ROSUVASTATIN PLUS CLOPIDOGREL is contraindicated in patients who are hypersensitive to either rosuvastatin or clopidogrel.
In patients with active liver disease including unexplained, persistent elevations of serum transaminases and any serum transaminase elevation exceeding 3 x the upper limit of normal (ULN).
In patients with severe renal impairment (creatinine clearance <30 ml/min).
In patients with myopathy.
In patients receiving concomitant ciclosporin.
During pregnancy and lactation and in women of childbearing potential not using appropriate contraceptive measures.
Active pathological bleeding such as peptic ulcer or intracranial hemorrhage.
