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Known hypersensitivity to naproxen or any other ingredient in the drug product.
History of asthma, urticaria or allergic-type reactions after taking aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs).
History of gastrointestinal bleeding or perforation related to previous NSAID therapy.
Active, or a history of, recurrent peptic ulcer or haemorrhage (two or more distinct episodes of proven ulceration or bleeding).
Severe heart failure.
