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No interaction studies have been performed.
Concurrent use of Golimumab (Simponi) with other biological therapeutics: The combination of Golimumab (Simponi) with other biological therapeutics used to treat the same conditions as Golimumab (Simponi), including anakinra and abatacept, is not recommended (see Precautions).
Live vaccines/therapeutic infectious agents: Live vaccines should not be given concurrently with Golimumab (Simponi) (Precautions and Use in Pregnancy & Lactation).
Therapeutic infectious agents should not be given concurrently with Golimumab (Simponi) (see Precautions).
Methotrexate: Although concomitant use of MTX results in higher steady‑state trough concentrations of Golimumab (Simponi) in patients with RA, PsA, or AS, the data do not suggest the need for dose adjustment of either Golimumab (Simponi) or MTX (see Pharmacology: Pharmacokinetics under Actions).
