Metformin hydrochloride (Sucranorm) is contraindicated in diabetic coma, ketoacidosis, hepatic or renal impairment, predisposition to lactic acidosis, severe infection or trauma, dehydration, alcohol dependence, deficiencies of Vitamin B12, folic acid and iron. Use of Metformin hydrochloride is not advised during pregnancy and lactation. Should not be given to patients with recent myocardial infarction, dehydration, or any other condition likely to predispose to lactic acidosis.
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