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Each film-coated tablet contains Tenofovir Alafenamide 25 mg equivalent to 28.043 mg (as Tenofovir Alafenamide Hemifumarate).
Tenofovir alafenamide hemifumarate is described chemically as Isopropyl N-{(S)-({[(2R)1-(6amino-9H-purin-9-yl}-2- propanyl]oxy}methyl)(phenoxy)phosphoryl]-Lalanfnate(2E)-2-butenedioate(2:1). The molecular formula is C46H62N12O14P12 and the molecular weight is 1068.39.
Tenofovir alafenamide hemifumarate is a white to off-white powder, and a pKa of 3.86. Soluble in dimethyl formamide and slightly soluble in methanol, sample was not hygroscopic (sample weight increased up to 0.07% to the original weight).
Excipients/Inactive Ingredients: Lactose monohydrate, Microcrystalline Cellulose, Croscarmellose sodium, Magnesium stearate, Opadry II Pink 85F94172, Purified water.
