Pharmacology:Pharmacokinetics: Terazosin is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration; the bioavailability is reported to be about 90%. Peak plasma concentrations are achieved in about one hour. It is metabolized in the liver; one of the metabolites is reported to possess antihypertensive activity. The half-life in plasma approximately 12 hours. It is excreted in feces via the bile, and in the urine as unchanged drug and metabolites. Terazosin is 90 to 94% protein bound.
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