Tozam Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Losartan K 50 mg, amlodipine besilate 5 mg

Indications/Uses

Mild to moderate HTN in case of inadequate control of monotherapy.

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Dosage/Direction for Use

1 tab once daily.

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Overdosage

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Administration

May be taken with or without food: Swallow whole, do not chew/crush.

Contraindications

Patients allergic to angiotensin receptor blocker or dihydropyridine Ca-channel antagonist.

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Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Tozam detailed prescribing information

Special Precautions

Symptomatic hypotension in patients w/ vol- &/or salt depletion. Discontinue therapy if patient developed jaundice or marked elevations of hepatic enzymes. Impaired liver & renal function. Pregnancy & lactation. Childn & adolescent <18 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Losartan K: Diarrhea, dyspepsia; muscle cramp, myalgia, back & leg pain; dizziness, insomnia; nasal congestion, cough, upper resp tract infection, sinus disorder, sinusitis. Amlodipine besilate: Edema, flushing, palpitation, fatigue, headache, somnolence, abdominal pain, dizziness.

Drug Interactions

Losartan K: Increase AUC w/ cimetidine. Potent inducers of CYP3A4. Increase in serum K w/ K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K.

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Storage

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Description

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Action

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MIMS Class

Angiotensin II Antagonists / Calcium Antagonists

ATC Classification

C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.

Regulatory Classification

Presentation/Packing

Form

Tozam FC tab

Packing/Price

100's (P2,860/pack)

Tozam

Manufacturer:

Torrent

Distributor:

Torrent