Tremfya Caution For Usage

Incompatibilities: Not applicable.
Instructions for Use and Handling and Disposal: Following administration of Guselkumab (Tremfya), discard any unused portion. The syringe should be disposed of using accepted medical practices for used syringes. The syringe and needle must never be re-used.
If the doctor decides that the patient or a caregiver may be able to give the injections of Guselkumab (Tremfya) at home, they should receive training on the right way to prepare and inject Guselkumab (Tremfya) using the pre-filled syringe before attempting to inject.
Please read the Instructions for Use before using the Guselkumab (Tremfya) pre-filled syringe and each time they get a refill. There may be new information. This instruction guide does not take the place of talking with a doctor about the medical condition or treatment. Please also read the Package Leaflet and instructions for administration carefully before starting the injection and discuss any questions the patient may have with a doctor or nurse.
Pre-filled pen: 1. Prepare for the injection: Inspect carton. Remove carton with the pre-filled pen from the refrigerator.
Keep pre-filled pen in the carton and let it sit on a flat surface at room temperature for at least 30 minutes before use.
Do not warm any other way.
Check the expiration date ('EXP') on the carton.
Do not use if the expiration date has passed.
Do not inject if perforations on the carton are broken.
Call a doctor or pharmacist for a new pre-filled pen.
Choose injection site: Select from the following areas for the injection: Front of thighs (recommended).
Lower abdomen: Do not use the 2-inch (5-centimetre) area around the belly-button.
Back of upper arms (if a caregiver is giving the injection).
Do not inject into skin that is tender, bruised, red, scaly, hard or has scars or stretch marks.
Wash hands: Wash hands well with soap and warm water.
Clean injection site: Wipe the chosen injection site with an alcohol swab and allow it to dry.
Do not touch, fan or blow on the injection site after you have cleaned it.
Inspect liquid in window: Take the pre-filled pen out of the carton.
Check the liquid in the window. It should be clear to slightly yellow and may contain tiny white or clear particles. You may also see one or more air bubbles.
This is normal.
Do not inject if the liquid is cloudy or discolored, or has large particles. If you are uncertain, call a doctor or pharmacist for a new pre-filled pen.
2. Inject Guselkumab (Tremfya) using the pre-filled pen: Twist and pull-off bottom cap: Keep hands away from the needle guard after the cap is removed.
Inject within 5 minutes of removing the cap.
Do not put the cap back on, this could damage the needle.
Do not use the pre-filled pen if it is dropped after removing the cap. Call a doctor or pharmacist for a new pre-filled pen.
Place on skin: Position the pre-filled pen straight onto the skin (about 90 degrees relative to injection site).
Push handle straight down: Medication injects as the patient push. Do this at a speed that is comfortable for the patient.
Do not lift the pre-filled pen during the injection. The needle guard will lock and the full dose will not be delivered.
Complete injection: Injection is complete when the handle is pushed all the way down, the patient will hear a click, and the teal body is no longer visible.
Lift straight up: The yellow band indicates that the needle guard is locked.
3. After the injection: Throw the used pre-filled syringe away: Put the used syringe in a sharps disposal container right away after use.
Make sure to dispose the bin as instructed by the doctor or nurse when the container is full.
Check injection site: There may be a small amount of blood or liquid at the injection site.
Hold pressure over the skin with a cotton ball or gauze pad until any bleeding stops.
Do not rub the injection site.
If needed, cover injection site with a bandage. The injection is now complete.