Adult 1-2 g daily as a single dose or in 2 divided doses. Severe infections Up to 4 g daily. Uncomplicated gonorrhea 250 mg single IM dose. Surgical infection prophylaxis Single dose of 1 g administered 0.5-2 hr before surgery. Colorectal surgery 2 g before surgery. Secondary cases of meningococcal meningitis 250 mg single IM dose. Childn & infant <50 kg 20-50 mg/kg once daily. Severe infections Up to 80 mg/kg daily. Neonates Max: <50 mg/kg IV over 60 mins daily. Secondary cases of meningococcal meningitis 125 mg as single dose.
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