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Adults: Initial Dose: 100 mg 3 times a day or 300 mg/day as a single dose.
If after strict cholesterol diet the concentration of cholesterol stays at >4 g/L, dose can be increased to 100 mg 4 times daily.
Initial dose should be maintained until cholesterol level gets back to normal. If cholesterol level stabilized, dosage of 100 mg twice daily can be given provided that the cholesterol level is checked every 3 months. If there is a new increase in the plasma cholesterol concentration, dose should go back to initial dose of 100 mg, 3 times daily.
