1st-line treatment of ovarian cancer 175 mg/m
2 as IV infusion for 3 hr followed by 75 mg/m
2 cisplatin & therapy is repeated at 3-wk intervals, or 135 mg/m
2 as IV infusion over a 24-hr period followed by 75 mg/m
2 cisplatin & therapy is repeated at 3-wk intervals.
2nd-line treatment of ovarian cancer 175 mg/m
2 over 3 hr infusion w/ a 3-wk interval between courses.
Adjuvant chemotherapy in breast carcinoma 175 mg/m
2 over 3 hr infusion every 3 wk for 4 courses following AC therapy.
1st-line chemotherapy of breast carcinoma 220 mg/m
2 IV over 3 hr w/ a 3-wk interval between courses in combination w/ doxorubicin 50 mg/m
2; administer paclitaxel 24 hr after doxorubicin. In combination w/ trastuzumab, paclitaxel 175 mg/m
2 IV over 3 hr w/ a 3-wk interval between courses.
2nd-line chemotherapy of breast carcinoma 175 mg/m
2 over 3 hr infusion w/ a 3-wk interval between courses.
Advanced NSCLC 175 mg/m
2 over 3 hr infusion followed by 80 mg/m
2 of cisplatin w/ a 3-wk interval between courses.
AIDS-related KS 100 mg/m
2 over 3 hr IV infusion every 2 wk.