Vsiqq

Vsiqq

brolucizumab

Manufacturer:

Novartis Pharma Stein

Distributor:

Novartis Healthcare
Concise Prescribing Info
Contents
Brolucizumab
Indications/Uses
Neovascular (wet) age‑related macular degeneration (AMD). Visual impairment due to diabetic macular edema (DME).
Dosage/Direction for Use
Intravitreal Wet AMD 6 mg (0.05 mL) by inj every 4 wk (mthly) for the 1st 3 doses, then administer every 12 wk (3 mth) thereafter. May individualize treatment intervals based on disease activity assessed by visual acuity &/or anatomical parameters. Treatment interval could be as frequent as every 8 wk (2 mth), however, interval between 2 doses should not be <8 wk (2 mth). DME 6 mg (0.05 mL) by inj every 6 wk for the 1st 5 doses, then administer every 12 wk (3 mth) thereafter. Treatment intervals should be based on disease activity as assessed by visual acuity &/or anatomic parameters. Patients w/ disease activity Consider treatment every 8 wk (2 mth).
Contraindications
Hypersensitivity. Active or suspected ocular or periocular infection, active intraocular inflammation.
Special Precautions
Endophthalmitis, retinal detachment/vasculitis &/or retinal vascular occlusion. Closely monitor patients who experience intraocular inflammation. Transient increase in IOP w/in 30 min of inj. Monitor both IOP & perfusion of optic nerve head. May experience temporary visual disturbance after inj & should be advised not to drive or use machinery until visual function has sufficiently recovered. Pregnancy. Breastfeeding is not recommended during treatment & for at least 1 mth after the last dose. Use effective contraception during treatment & for at least 1 mth after the last dose in females of reproductive potential. Childn <18 yr.
Adverse Reactions
Reduced visual acuity, retinal haemorrhage, uveitis, iritis, vitreous detachment/floaters, retinal tear, cataract, conjunctival haemorrhage, eye pain, increased IOP, conjunctivitis, retinal pigment epithelial tear, blurred vision, corneal abrasion, punctate keratitis; hypersensitivity.
MIMS Class
Other Eye Preparations
ATC Classification
S01LA06 - brolucizumab ; Belongs to the class antineovasculatisation agents. Used in the management of neovascular macular degeneration.
Presentation/Packing
Form
Vsiqq soln for inj 120 mg/mL
Packing/Price
(single use, type 1 colourless glass w/ grey rubber stopper and aluminum seal w/ violet flip-off cap + 1 filter needle in soft blister) 2 mL x 1's
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