Oxymetazoline-containing nasal sprays should not be used: In patients with known hypersensitivity to oxymetazoline or other adrenergic agents, or to any component of the medicinal product; in patients taking monoamine oxidase inhibitors (MAOIs) or in patients who have taken MAOIs in the previous two weeks; in patients with narrow-angle glaucoma; in patients after trans-sphenoidal hypophysectomy; where there is inflammation of the skin and mucosa of the nasal vestibule and encrustation (rhinitis sicca); in patients with acute cardiovascular disease or cardiac asthma; in patients with severe high blood pressure.
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