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Use in Pregnancy: When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, Irbesartan should be discontinued as soon as possible.
Hypersensitivity to any component of the product (see Description).
Second and third trimester of pregnancy (see Precautions and Use in Pregnancy & Lactation).
Lactation (see Use in Pregnancy and Lactation).
Do not co-administer Converium with aliskiren-containing medicines in patients with diabetes or with moderate to severe renal impairment (glomerular filtration rate (GFR) <60 ml/min/1.73 m2) (see Precautions and Interactions).
Do not administer Converium with angiotensin-converting enzyme inhibitors (ACEIs) in patients with diabetic nephropathy (see Precautions and Interactions).
