Active booster immunization for the prevention of DPT in persons ≥4 yr. Passive protection against pertussis in early infancy following maternal immunization during pregnancy. Alternative for the 5th dose of tetanus, diphtheria & acellular pertussis vaccine (DTaP) in childn 4-6 yr. Tetanus prophylaxis in wound management.
IM Administer 0.5 mL as booster dose. Preferred site is into deltoid muscle. Re-dosing may be used at 5- to 10-yr intervals. May be administered to pregnant women during 2nd or 3rd trimester.
View Adacel overdosage for action to be taken in the event of an overdose.
Contraindications
Hypersensitivity. Life-threatening reaction after previous administration of the vaccine or a vaccine containing ≥1 of the same components. Encephalopathy (eg, coma, decreased level of consciousness, prolonged seizures) w/in 7 days of previous dose of any pertussis-containing vaccine.
Hypersensitivity reactions. Do not administer by intravascular, intradermal or SC route or into the buttocks. Do not use for the treatment of disease caused by Bordetella pertussis, Corynebacterium diphtheriae or Clostridium tetani infections. Postpone vaccination in case of acute or febrile disease. Not to be administered in patients w/ any bleeding disorders eg, hemophilia or thrombocytopenia, or on anticoagulant therapy. Delay vaccination in immunocompromised patients until after any immunosuppressive treatment completion. Not to be administered to individuals w/ progressive or unstable neurological disorders, uncontrolled epilepsy or progressive encephalopathy until treatment regimen is established. Guillain-Barré syndrome w/in 6 wk prior to vaccination. Pregnancy & lactation. Infants born to women vaccinated w/ Adacel during pregnancy. Childn <4 yr.
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