Cefper Caution For Usage

INCOMPATIBILITIES: Aminoglycosides: Solution of CEFPER and aminoglycosides should not be directly mixed, since there is a physical incompatibility between them. The combination therapy can be accomplished by sequential intermittent intravenous infusion provided that separate secondary intravenous tubing is used, and the primary intravenous tubing is adequately irrigated with an appropriate diluent between doses. It is also suggested that each dose of CEFPER should be administered as far as the dose of aminoglycosides infusion as possible.
Lactated Ringer's solution: Lactated Ringer's solution should not be used for initial reconstituted solution. Sterile water for injection should be used for initial reconstitution then further diluted with Lactated Ringer's solution to obtained Sulbactam concentration of 5 mg/ml.
Lidocaine: 2% lidocaine should not be used for initial reconstituted solution since the mixture has been shown to be incompatible. However, initial reconstitution in sterile water for injection and further dilution with 2% lidocaine to obtain solutions of 0.5% lidocaine will result in a compatible mixture.