Clinda-VC Special Precautions

It is contra-indicated in patients who are hypersensitive to clindamycin or lincomycin.
Aminoglycosides are associated with clindamycin significance nephrotoxicity and ototoxicity.
It should be used with caution in patient who have a history of gastrointestinal disease, particularly ulcerative colitis, or severe hepatic function impairment.
Monitoring of renal and 8^th cranial nerve function at onset of therapy and at regular interval are essential especially for patients with suspected renal impairment.
Avoid concomitant use with other ototoxic, neurotoxic or nephrotoxic drugs.
Dehydration and advanced age may increase risk of toxicities.
Use in Children: Benzyl alcohol in the product has been associated with a fatal 'gasping syndrome' in premature infants.
Not recommended for use in children under 2 years of age.
Use in Pregnancy: Avoid using clindamycin in pregnant woman (Category D) unless benefit outweighs the risk.