ClinOleic Caution For Usage

INCOMPATIBILITIES: Complete information about incompatibilities is not available.
Do not add medication or electrolytes directly to the lipid emulsion. If it is necessary to introduce additives, verify the compatibility and mix thoroughly before administration to the patient.
INSTRUCTIONS FOR USE/HANDLING AND DISPOSAL: BOTTLE: Before opening the protective overwrap, check the color of the oxygen indicator affixed to the oxygen absorber. Compare it to the reference color printed next to the OK symbol and depicted in the printed area of the indicator label. Do not use the product if the color of the oxygen indicator does not correspond to the reference color printed next to the OK symbol.
All opened bottles must be used immediately and not be stored for further use.
For single use only. Discard partly use bottle.
BAG: To open: Remove the protective overwrap. Discard the oxygen absorber/indicator.
Confirm the integrity of the bag.
Use only if the bag is not damaged and if the emulsion is a homogeneous liquid with a milky appearance.
Once the bag is opened, use immediately. Discard partially used containers.
Positioning the infusion: Suspend the bag.
Remove the plastic protector from the administration outlet.
Firmly insert the infusion spike into the administration outlet.
Additions: Do not make any additions directly to the bag.
If it is necessary to introduce additives, verify the compatibility and mix thoroughly before administration to the patient.
Additions must be performed under aseptic conditions. These additions are made into the injection site using a needle: Prepare the injection site.
Puncture the injection site and inject.
Mix the contents of the bag and the additives.
Administration: For single use only.
Do not store partially used bags and destroy all accessory parts after use.
Do not re-connect partially used bags.
Do not connect a bag in series in order to avoid the possibility of air embolism due to gas contained in the first bag.
Any unused product or waste material and all necessary disposable devices must be discarded.
When used in neonates and children below 2 years, protect from light exposure when admixtures include trace elements and/or vitamins, after admixture through administration. Exposure of CLINOLEIC 20% to ambient light after admixture generates peroxides and other degradation products that can be reduced by photoprotection (Precautions).
When administered as a component of parenteral nutrition, the compatibility of the components and stability of the admixture must be checked before administration to the patient. Admixing should be accompanied by gentle agitation during preparation under strict aseptic conditions.
When preparing an admixture that includes CLINOLEIC 20%, the final osmolarity of the mixture should be measured before administration via a peripheral vein.
If the final mixture is hypertonic, it may cause irritation of the vein when administered into a peripheral vein.