Epilepsy, patients w/ history of seizures, emotional disturbances or suicidal ideation or attempts, risk for resp depression. Increased intracranial pressure or head trauma. Concomitant use of serotonergic drugs eg, SSRIs, SNRIs, TCAs, MAOIs, triptans & alcohol; w/drawal symptoms upon abrupt discontinuation. Hepatic impairment. May affect ability to drive or operate machinery. Pregnancy & lactation.
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