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Hypersensitivity to the active substance or to any of the excipients (see Description).
Concomitant treatment with other monoamine oxidase (MAO) inhibitors (see Precautions and Interactions).
Concomitant treatment with pethidine (see Precautions and Interactions).
Use in patients with severe hepatic impairment (see Dosage & Administration).
Use in patients with albinism, retinal degeneration, uveitis, inherited retinopathy or severe progressive diabetic retinopathy (see Precautions and PHARMACOLOGY: Toxicology: Preclinical safety data under Actions).
