Sign Out
Posology: Treatment with safinamide should be started at 50 mg per day. This daily dose may be increased to 100 mg/day on the basis of individual clinical need.
If a dose is missed the next dose should be taken at the usual time the next day.
Elderly: No change in dose is required for elderly patients.
Experience of use of safinamide in patients over 75 years of age is limited.
Hepatic impairment: Safinamide use in patients with severe hepatic impairment is contraindicated (see Contraindications).
No dose adjustment is required in patients with mild hepatic impairment. The lower dose of 50 mg/day is recommended for patients with moderate hepatic impairment. If patients progress from moderate to severe hepatic impairment safinamide should be stopped (see Precautions).
Renal impairment: No change in dose is required for patients with renal impairment.
Paediatric population: The safety and efficacy of safinamide in children and adolescents under 18 years of age have not been established. No data are available.
Method of administration: For oral use.
Safinamide should be taken with water.
Safinamide may be taken with or without food.
