EXSIROX (250 mg) is contraindicated in: Patients with known hypersensitivity to Deferasirox or any component of this formulation.
Patients with creatinine clearance < 40 ml/min or serum creatinine > 2 times the age-appropriate ULN.
Patients with poor performance status.
Patients with high-risk myelodysplastic syndromes.
Patients with advanced malignancies.
Patients with platelet counts < 50,000/mm3.