Ototoxic and Nephrotoxic Drugs: Because of the possibility of additive toxicities, the concurrent or sequential systemic or topical use of other ototoxic and/or nephrotoxic drugs (e.g., aminoglycosides, amphotericin B. bacitracin, cisplatin, colistin, polymyxin B) and vancomycin requires careful monitoring of renal and auditory functions; these drugs should be used with caution in patients receiving vancomycin therapy.
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