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Glufast

Glufast

Manufacturer:

Eisai

Distributor:

DKSH
Concise Prescribing Info
Contents
Mitiglinide Ca hydrate
Indications/Uses
Improvement in postprandial plasma glucose transition in patients w/ type 2 DM w/ inadequate response to dietary treatment & exercise therapy alone, or use of α-glucosidase inhibitors in addition to diet & physical exercise.
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Dosage/Direction for Use
Adult 1 tab tid.
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Overdosage
View Glufast overdosage for action to be taken in the event of an overdose.
Administration
Should be taken with food: Take w/in 5 min before meals.
Contraindications
History of hypersensitivity. Severe ketosis, diabetic coma or precoma, type 1 DM, severe infections, before or after surgery, or serious trauma. Women who are pregnant or may possibly be pregnant.
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Special Precautions
Not indicated to diseases w/ diabetes-like symptoms eg, renal diabetes, senile glycometabolic disorder & abnormal thyroid function. Administer only in patients w/ fasting blood glucose level ≥126 mg/dL or postprandial blood glucose level ≥200 mg/dL w/in 1 or 2-hr period. Ischemic heart disease, pituitary or adrenal insufficiency, gastroenteropathy (eg, diarrhea & vomiting), malnutrition, starvation, insufficient food intake, debility. Strenuous physical exercise, excessive alcohol ingestion. Periodically monitor blood glucose level & condition. Should not be concomitantly used w/ sulfonylurea-type agents. Concomitant use w/ insulin sensitizer (eg, pioglitazone HCl) or biguanides (eg, metformin). Hepatic & renal dysfunction. May impair ability to drive or operate machinery. Contraindicated in pregnancy. Avoid in lactating women. Childn. Elderly.
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Adverse Reactions
Hypoglycemic symptoms (eg, dizziness, hunger pangs, tremor, feeling of weakness, cold sweat, decreased consciousness, malaise, palpitations, dull headache, bleary-eyes feeling, nausea, feeling bad, numbness, sleepiness, difficulty in walking, yawning); increased pyruvic acid, AST (GOT), γ-GTP, lactic acid, ALT (GPT) & free fatty acid; abdominal distension, constipation, diarrhea, headache.
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Drug Interactions
May enhance hypoglycemic effect w/ insulin prep, biguanides (eg, metformin), α-glucosidase inhibitors (eg, voglibose), insulin sensitizer (eg, pioglitazone HCl), salicylates (eg, aspirin), clofibrate, sulfanilamide (eg, sulfamethoxazole), β-adrenergic blocking agents (eg, propranolol), MAOIs, anabolic hormone (eg, mestanolone), tetracyclines (eg, tetracycline HCl, minocycline HCl). May reduce hypoglycemic effect w/ epinephrine, adrenocortical hormones (eg, methylprednisolone), ovarian hormones (eg, ethinylestradiol) & thyroid hormones, nicotinic acid, INH, pyrazinamide, phenothiazines (eg, chlorpromazine), diuretics (eg, thiazide, chlorthalidone, ethacrynic acid), phenytoin, guanethidine sulphate.
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Caution For Usage
For caution against possible variation of physical aspect of medicine... Click to view Glufast detailed prescribing information
Storage
View Glufast storage conditions for details to ensure optimal shelf-life.
Description
View Glufast description for details of the chemical structure and excipients (inactive components).
Action
View Glufast mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Antidiabetic Agents
ATC Classification
A10BX08 - mitiglinide ; Belongs to the class of other blood glucose lowering drugs excluding insulins. Used in the treatment of diabetes.
Presentation/Packing
Form
Glufast tab 10 mg
Packing/Price
3 × 10's
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