Adults: (including the elderly).
Knee and Hip Osteoarthritis: The contents of one vial (20 mg/2 mL) or prefilled syringe (20 mg/2 mL) to be injected into the affected joint once a week for a total of three to five injections, using a standard technique. No adjustment of dose is required in elderly patients. This can be repeated at not less than 6 monthly intervals.
Ankle Osteoarthritis: Inject one milliliter of 20 mg/2 mL solution from the vial or prefilled syringe into the affected joint once weekly for a total of five injections, using a standard technique. No adjustment of dose is required in elderly patients. This can be repeated at not less than 6 monthly intervals.
Shoulder Osteoarthritis: Inject the contents of one vial or prefilled syringe (20 mg/2 ml) into the affected joint with a three-day interval between each injection for a total of three injections, using a standard technique. No adjustment of dose is required in elderly patients.
Children: At present there is not enough evidence to recommend a dosage regimen for use in children.