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Pregnancy: In rats and rabbits, Paclitaxel was shown to result in abortions, decreased corpora lutea, a decrease in implantation and live fetuses, increased reabsorptions and embryo-fetal deaths. No gross external, soft issue or skeletal alterations occurred.
There are no studies in pregnant women. If INTAXEL is used during pregnancy, or if the patient becomes pregnant while receiving this drug, the patient should be apprised of the potential hazard. Women of childbearing potential should be advised to avoid becoming pregnant during therapy with INTAXEL.
Nursing mothers: It is not known whether the drug is excreted in human milk. Because many drugs are excreted in human milk and because the potential for serious adverse reactions in nursing infants, it is recommend that nursing be discontinued when receiving Intaxel therapy.
