Metadoxil Mechanism of Action

Pharmacology: Pharmacodynamics/Pharmacokinetics: Metadoxine antagonizes the lipid peroxidation in liver cells, restoring liver damage resulting from prolonged alcohol intake and reduces fatty liver in chronic hepatitis.
Furthermore metadoxine acts specifically on the neurotransmitter systems involved in alcoholic intoxication, increasing the release of GABA and acetylcholine.
Metadoxine improves ethanol metabolism, reducing plasma ethanol levels during alcohol intake and improves the cognitive impairment, as well as the main psychological symptoms (aggressiveness, agitation, mood and behavioral disturbances) due to occasional or prolonged alcohol abuse.
Therapeutic Efficacy: METADOXIL Tablet reduces the stay-time of ethanol in the organism, thus minimizing its toxic effects on cells.
METADOXIL Tablet also protects cell structure and function, acting on those biochemical processes which defend them.
Due to these peculiar pharmacological properties, METADOXIL Tablet reduces detoxification time in acute ethanol intoxication and prevents or reduces the hepatic and neuropsychic consequences of habitual intake of alcohol.