METADOXIL Tablet is white round tablet with a score-line on one side and METADOXIL engraved on the other.
Each tablet contains Metadoxine (pyridoxine L-2-pyrrolidone-5-carboxylate) 500 mg.
Pharmacology: Pharmacodynamics/Pharmacokinetics: Metadoxine antagonizes the lipid peroxidation in liver cells, restoring liver damage resulting from prolonged alcohol intake and reduces fatty liver in chronic hepatitis.
Furthermore metadoxine acts specifically on the neurotransmitter systems involved in alcoholic intoxication, increasing the release of GABA and acetylcholine.
Metadoxine improves ethanol metabolism, reducing plasma ethanol levels during alcohol intake and improves the cognitive impairment, as well as the main psychological symptoms (aggressiveness, agitation, mood and behavioral disturbances) due to occasional or prolonged alcohol abuse.
Therapeutic Efficacy: METADOXIL Tablet reduces the stay-time of ethanol in the organism, thus minimizing its toxic effects on cells.
METADOXIL Tablet also protects cell structure and function, acting on those biochemical processes which defend them.
Due to these peculiar pharmacological properties, METADOXIL Tablet reduces detoxification time in acute ethanol intoxication and prevents or reduces the hepatic and neuropsychic consequences of habitual intake of alcohol.
Recommended Dose: One tablet twice a day (morning and evening).
Mode of Administration: Oral.
Overdose and Treatment: No case of overdose with metadoxine has been reported; therefore no experience on overdose is available. In case of overdose the patient should be supervised and symptomatic treatment should be instituted.
Known hypersensitivity to the preparation.
Caution must be exercised in Parkinsonians treated with L-Dopa, as METADOXIL Tablet may antagonize the drug's effect.
METADOXIL Tablet should not be used during pregnancy or lactation.
The reported undesirable effects occurred very rarely (less than 1 in 10,000 patients): hypersensitivity, peripheral neuropathy, dizziness, disorientation, diarrhoea, vomiting, angioedema, rash, urticaria, pruritus, decreased appetite.
METADOXIL Tablet may reduce the therapeutic effectiveness of L-Dopa.
A05BA09 - metadoxine ; Belongs to the class of drugs used in liver therapy.
Metadoxil tab 500 mg
100's
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