Enzyme-inducing drug can cause failure of Minidoz. This effect is well established for a number of antiepileptics (e.g. phenytoin, barbiturates, phenobarbital, primidone, carbamazepine, oxcarbazepine, felbamate, topiramate), griseofulvin, antibacterials (e.g. rifampicin, rifabutin, penicillins), antidepressants (St. John's wort), and also been suggested for some antivirals (e.g. neflinavir, ritonavir) and for modafinil.
Inform the doctor or pharmacist if the patient is taking, or has recently taken, any other medicines, even those not prescribed.