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Pregnancy: Norepinephrine is classified as FDA pregnancy risk category C (Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus). Easily crosses the placenta, and may stimulate uterine contractions or constrict uterine blood flow, leading to fetal hypoxia.
Lactation: It is not known whether norepinephrine is excreted into human breast milk. Use caution when considering the use of norepinephrine in lactating women.
