Diseases caused by disturbances in the Ca metabolism in consequence of reduced endogenous production of 1.25-dihydroxyvit D3. Renal osteodystrophy, post-op or idiopathic hypoparathyroidism, pseudohypoparathyroidism, as an adjunct to the management of tertiary hyperparathyroidism, vit D-resistant rickets or osteomalacia, vit D-dependent rickets, neonatal hypocalcaemia or rickets, malabsorption of Ca, osteoporosis, malabsorptive & nutritional rickets & osteomalacia.
Monitor serum Ca & serum phosphate levels regularly; PTH, alkaline phosphatase, & Ca phosphate product. Avoid prolonged hypercalcaemia in arteriosclerosis, cardiac valve sclerosis or nephrolithiasis. Patients w/ calcification of pulmonary tissue, granulomatous diseases eg, sarcoidosis; renal bone disease or severely reduced renal function. Concurrent use of digitalis glycosides in the presence of hypercalcaemia. Sesame oil allergy. May affect the ability to drive & use machines. Pregnancy & lactation.
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