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Gastroesophageal reflux disease: Intravenous infusion 40 mg at a rate of 3 mg (7 mL) per minute over approximately fifteen minutes each day for seven to ten days.
Pathologic GI hypersecretory conditions: Intravenous infusion 80 mg at a rate of 3 mg (7 mL) per minute over approximately fifteen minutes every 12 hours. Dosing frequency can be adjusted to individual patient needs base on acid output, measurements. In those patients needing a higher dose, 80 mg every 8 hours is expected to maintain acid output below 10 mEq per hour.
Note: Dosage adjustments are not necessary in patients with renal or hepatic impairment or in patients undergoing hemodialysis.
Treatment with Pantoprol should be discontinued as soon as the patient is able to resume taking pantoprazole delayed-release.
