Phez Special Precautions

The cardiovascular status of the patient should be considered before Phenylephrine is administered.
The drug should be used with caution in patients with marked hypertension, cardiac disorders, advanced arteriosclerotic changes, type 1 (insulin-dependent, IDDM) diabetes mellitus or hyperthyroidism. Blood pressure should be carefully monitored if the Phenylephrine hydrochloride 10% is used in these patients or in other patients who develop symptoms.
Phenylephrine should be administered with caution to patients at increased risk of adverse systemic effects of the drug.
Increased risk of vasopressor response with higher than recommended doses, or with application to instrumented (e.g. tonometry), traumatized, diseased, or postsurgical eye or adnexa, or with reduced lacrimation during anesthesia.
Rebound miosis is reported in older patients within one day; caution is advised to monitor for this effect in patients undergoing retinal detachment or cataract surgery.
Phenylephrine ophthalmic solutions should not be used in patients with soft contact lenses.
Risk of precipitating severe hypertension.
Do not use Phenylephrine hydrochloride solution if brown or contains a precipitate.